ProQR Uses Causaly to Support Target Identification For Axiomer™ Platform
ProQR faced challenges with bandwidth, aggressive targets, and the overwhelming growth of biomedical literature. Causaly's AI platform accelerated ProQR’s R&D by enabling faster review of publications and allowing their team to make more informed decisions. Read the case study below to learn how ProQR met their 2024 target ID goal by Q3 and achieved 5x productivity compared to using PubMed.
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Challenges before Causaly
Limited Bandwidth
ProQR’s R&D team is responsible for multiple projects, so they often juggle multiple research streams.
Ambitious Target Hunting Goals
ProQR was looking to identify many high conviction targets to demonstrate breadth of application of their Axiomer™ platform.
Cutting through the Noise
With the exponential growth of biomedical literature, ProQR wanted to ensure they weren’t missing critical evidence.
Causaly helped us unearth more hidden links much faster than if we were to go through the paper, read it, and hope the author mentions what we are interested in. PubMed wouldn’t be a substitute. - Bart Klein, SVP Head of Axiomer Strategy
Causaly solutions
Faster R&D
ProQR quickly reviewed many more publications with AI-generated summaries, to explain relationships and phenomena they had observed in studies, accelerating progress within their current pipeline at a rate that was previously not possible with PubMed.

Uncovering New Insights
Using Causaly’s high-precision knowledge graph, ProQR was able to find hidden connections and facilitate the identification of target indications already in the pipeline while also revealing new research angles.

Stronger, More Informed Decisions
ProQR accelerated target ID and selection processes and uncovered critical insights around safety concerns, which helped them make go/no-go decisions during target validation.
The results
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2024 target ID goal met by Q3
50% of the targets ProQR pitched in Q3 were informed by Causaly insights
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5x more productive than using PubMed
AI capabilities enabled review of more relevant and higher number of publications
Further reading
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