Enzyme

Exploring Biochemical Pathways with Human-Centric AI

In drug development, understanding biochemical pathways is essential for elucidating molecular mechanisms in cells and tissues, thereby informing targeted therapeutic strategies. In this example, we used Causaly to identify and explore biochemical pathways affected by targets for acute kidney injury (AKI).

Written by
Elizabeth Bolitho
  • Categories
  • Disease Pathophysiology
  • Target Selection
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Overview

Identifying Targets for AKI

Exploring Biochemical Pathways with Human-Centric AI image 0
Figure 1: Dendrogram view of targets for AKI.

Prioritization of Targets in Porcine Models

Pathways Affected by NOX2 and NOX4

Comparative Analysis: NOX2 vs. NOX4

Exploring Biochemical Pathways with Human-Centric AI image 0
Figure 2: Comparative analysis of pathways affected by NOX2 and NOX4. Data retrieved on 15/12/2023.

Conclusion

References

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