Preclinical Toxicologists
As a preclinical toxicologist, your expertise is crucial during preclinical discovery, where you ensure the efficacy and safety of potential therapeutic compounds before they reach clinical trials. Our platform is designed to help you decipher target biology, resolve conflicting data, foresee potential safety concerns, and construct comprehensive experiments with ease and precision. With Causaly, uncover intricate toxicological profiles, identify hidden safety risks, and generate actionable insights faster than ever before. Join us in expediting preclinical development and transforming toxicity prediction, driving the future of safety pharmacology and contributing to breakthroughs in life sciences.
Decode Target Biology
Use AI to uncover unintended effects due to on-target or off-target activity hidden in the literature.
Comprehensive Understanding
Analyze scientific data extensively to enhance your understanding of target biology and its implications for safety and toxicology.
Hidden Connection Discovery
Uncover hidden connections within the data and reveal key insights about target biology that might otherwise remain unnoticed.
Efficiency Improvement
Navigate through the vast scientific data at speed and significantly accelerate your target safety assessment.
Reconcile Evidence
Get a balanced view of the evidence, to form more robust hypotheses.
Evidence Resolution
Navigate the scientific data efficiently, resolve contradictory evidence and enhance the robustness of your safety assessments.
Accuracy Enhancement
Cross-verify research findings from various studies to decrease the chance of erroneous conclusions due to conflicting evidence.
Design Experiments
Use historical insights to design safety studies that can be translated from animal models to humans.
Experiment Design
Safety and toxicology scientists utilize Causaly to design comprehensive experiments, employing its vast literature analysis to identify critical factors and anticipate potential outcomes.
Hypothesis Enhancement
Leveraging Causaly, scientists can bolster their hypotheses with extensive prior research which leads to more robust and targeted experimental designs.
Risk Mitigation
Scientists use Causaly to predict potential challenges and devise strategies to avoid them. That enhances the reliability and success rate of their experimental designs.
Streamline Safety Assessment
Conduct an in-depth evaluation of target safety, including broad evidence from tissue expression and knockout studies.
Rapid Assessment
Scan and analyze the biomedical literature quickly and streamline the process of target safety assessment.
Comprehensive Review
Access a holistic view of the safety profile of targets and identify potential issues that might have been overlooked in conventional reviews.
Efficiency Boost
Increase your productivity by refining safety assessments in a more time-efficient manner, while ensuring thorough analysis.
Mitigate Risks
Identify specific areas of focus in exploratory studies based on early safety insights.
Informed Decision-making
Make informed decisions when developing safety risk mitigation strategies by accessing a comprehensive analysis of safety-related information from diverse biomedical literature.
Proactive Risk Identification
Identify potential safety risks associated with targets or drug candidates proactively and enable the development of effective risk mitigation strategies at an early stage.
Evidence-based Approach
Use an evidence-based approach to develop safety risk mitigation strategies to ensure decisions are grounded in a thorough analysis of relevant literature and data.
Decode Target Biology
Use AI to uncover unintended effects due to on-target or off-target activity hidden in the literature.Comprehensive Understanding
Analyze scientific data extensively to enhance your understanding of target biology and its implications for safety and toxicology.
Hidden Connection Discovery
Uncover hidden connections within the data and reveal key insights about target biology that might otherwise remain unnoticed.
Efficiency Improvement
Navigate through the vast scientific data at speed and significantly accelerate your target safety assessment.
Preclinical Toxicologist Resources
View More
Pharmacogenomic Insights: Temozolomide in Glioblastoma
Pharmacogenomics is an emerging field that combines pharmacology and genomics to identify genetic factors influencing individual responses to medications. This innovative approach opens doors to more effective and personalized therapies, promoting patient safety and providing tailored treatment options.
Exploring the Latest Developments in Multiple Sclerosis: A 5-Year Overview
As we celebrate World MS Day on 30th May 2023, it’s a great opportunity to reflect on the significant strides that have been made in MS research over the past 5 years.
Causaly vs PubMed®: 2x as many relevant articles identified by Causaly using the same data
: Medical Affairs, Regulatory and Pharmacovigilance experts are interested in identifying all the available evidence related to a drug’s safety profile. In order to accurately conduct a drug safety assessment, the relevance of results is pivotal, given the vast amount of data sources and time limitations.
Full-text vs Abstract advantage: Causaly identifies 3x as many relevant articles by machine-reading the full-text
Literature research is an ongoing, iterative process for all scientists. A literature review is a large task that can require 60–80 hours of focused effort for regulatory professionals (1). This includes scanning the medical literature to collect adverse events and analyzing the results.
Preclinical safety analysis using Artificial Intelligence on the example of Alzheimer’s Disease.
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that currently produces dementia in 5.8 million U.S citizens. This number is projected to reach 13.5 million by 2050 highlighting the urgent need for means to prevent, delay the onset, slow the progression and improve the symptoms of AD (1).
Using AI to answer clinical questions: COPD Case Studies
Chronic Obstructive Pulmonary Disease (COPD) describes a group of conditions which cause breathing difficulties, and includes chronic bronchitis and emphysema. The condition mainly affects older people who smoke and is typically managed by clinicians and other health professionals in a primary care setting.